How to watch Bills vs Lions: NFL, live stream, TV channel, start time
· Yahoo Sports
The Buffalo Bills host the Detroit Lions on Thursday Night Football in a Week 2 showdown between two teams that escaped opening weekend with victories. Buffalo beat the Houston Texans 36-31, while Detroit held off the New Orleans Saints 31-30.
Dec 21, 2025; Detroit, Michigan, USA; Detroit Lions running back Jahmyr Gibbs (0) warms up before the game against the Pittsburgh Steelers at Ford Field. Mandatory Credit: Lon Horwedel-Imagn ImagesHow to Watch Bills vs Lions
- When: Thursday, September 17, 2026
- Time: 8:15 PM ET
- TV Channel: Prime Video
- Live Stream: Prime (try for free)
Josh Allen and the Bills will get their first home game of the season after an explosive opener in Houston. Buffalo’s offense features Allen alongside reigning rushing champion James Cook and new addition DJ Moore, giving the Lions a difficult assignment after Detroit surrendered 30 points in Week 1.
Visit betsport.cv for more information.
– Live stream Bills vs Lions with Prime –
Jared Goff leads a Detroit offense that can answer with plenty of firepower of its own, including Jahmyr Gibbs, Amon-Ra St. Brown and Jameson Williams. Thursday’s matchup carries some extra significance for Buffalo, as it will be the first regular-season game played at the new Highmark Stadium. Kickoff is set for 8:15 PM ET on Prime Video.
This is a great NFL matchup you will not want to miss; make sure to tune in and catch all the action.
Live stream Bills vs Lions on Prime: Start your free trial now!
Prime Video is a must-have for NFL fans, serving as the exclusive home of Thursday Night Football throughout the season. Sign up for Prime with a 30-day free trial to stream marquee NFL matchups live each Thursday while also getting access to a huge library of movies, shows, and other sports.
Watch every regular season NFL game with Sunday Ticket on YouTube TV
Regional restrictions may apply. If you purchase a product or register for an account through one of the links on our site,
— Enjoy free coverage of the top news & trending stories on The Big Lead —